Correlation of Atrial Fibrillation with Left Atrial Volume in Patients with Mitral Stenosis. a Single Centre Study From Pakistan

Background: Rheumatic heart disease has a strong association with mitral valve stenosis. Atrial fibrillation is one of the most common complications of this condition and is a poor prognostic factor. Early detection and prompt management of atrial fibrillation can help to improve the quality of life and increase the life expectancy of the patients. We carried out this study to investigate the significance of left atrial volumetric changes in mitral stenosis and its correlation with atrial fibrillation. Methodology: We audited the data of 60 patients of rheumatic heart disease who had mitral valve stenosis. The patients were randomized into atrial fibrillation (Group A) and normal sinus rhythm (Group B). We conducted this cross-sectional analytical study at Cardiology Department, Mayo Hospital, Lahore, from 1st February 2017 to 31st January 2018. We only included those patients who consented to be a part of this study and fulfilled our predefined inclusion criteria. Left atrial volume was measured by prolate ellipse method and biplane methods on echocardiography. The Data was analyzed on SPSS v20. Results: Sixty patients were included in the study. Among the subjects, thirty-six (60%) were males, and twenty-four (40%) were females. Atrial fibrillation was noted in 43.33% of the patients of mitral valve stenosis. There was a marked difference in the mean volume of the left atrium among the two groups. We observed that the mean area of the mitral valve for Group A patients was larger than that of patients in Group B. Our study showed an inverse correlation between left atrial volume and mitral valve area among Group A patients. Conclusion: Patients of mitral stenosis are at an increased risk of developing atrial fibrillation if the left atrial volume is increasing. All patients with mitral stenosis should have routine echocardiography & measurement of left atrial volumes, so that proper treatment can be started if the left atrial volume is increasing, to prevent atrial fibrillation

Aplikasi Rekomendasi Pola Makan Berbasis IOS

The goal for implementing this system is to help users manage and track history about their eat pattern, choose proper food for body\u27s need, and pick restaurants. Methodology used for this research contains three parts, which is analysis, design, and literature study. In requirement analysis, we do some interview with nutritionist and food provider, analysis iOS user, compare with same kind of application, and identify components that we need. In design method, we use Unified Modelling Language approach, ERD design, and user interface design. The result is a food planning mobile application with iOS platform. This application can help user manage and track their eat pattern, help user choose balanced food that suitable for their body, and inform user where they can get food they plan to eat

Robustness of Cosmological Simulations I: Large Scale Structure

The gravitationally-driven evolution of cold dark matter dominates the formation of structure in the Universe over a wide range of length scales. While the longest scales can be treated by perturbation theory, a fully quantitative understanding of nonlinear effects requires the application of large-scale particle simulation methods. Additionally, precision predictions for next-generation observations, such as weak gravitational lensing, can only be obtained from numerical simulations. In this paper, we compare results from several N-body codes using test problems and a diverse set of diagnostics, focusing on a medium resolution regime appropriate for studying many observationally relevant aspects of structure formation. Our conclusions are that -- despite the use of different algorithms and error-control methodologies -- overall, the codes yield consistent results. The agreement over a wide range of scales for the cosmological tests is test-dependent. In the best cases, it is at the 5% level or better, however, for other cases it can be significantly larger than 10%. These include the halo mass function at low masses and the mass power spectrum at small scales. While there exist explanations for most of the discrepancies, our results point to the need for significant improvement in N-body errors and their understanding to match the precision of near-future observations. The simulation results, including halo catalogs, and initial conditions used, are publicly available.Comment: 32 pages, 53 figures, data from the simulations is available at http://t8web.lanl.gov/people/heitmann/arxiv, accepted for publication in ApJS, several minor revisions, reference added, main conclusions unchange

Comparative studies on mydriatic effect of tropicamide 0.8% and phenylephrin 5.0% in teenagers & geriatric people

Prospective study on the comparison of mydiriatic effect of Tropicamide 0.8% and Phenylephrine 5% in teenagers and geriatric people was carried out in suthrama Eye Hospital madanapalle, India. The main objective of this study was to compare the mydriatic effect of a combination of drug in teenagers and geriatric people. It also evaluated the ADR’s produced and the efficacy of the drug in two age groups. In this study population majority of the subjects were female in group A and male in group B. Among the whole population under study in group A and B no one has reported with any case of congenital anomalies. A number of ADR’s are reported but no serious adverse events had occurred. The study was carried out in 100 eyes ie. 50 subjects whom are divided into 2 groups based on age. The comparison of mydriatic effect was done in each group after instilling one drop of a combination of 0.08% Tropicamide and 0.5% Phenynilephrine. The pupillary size where measured before and after administration of drug and the results were compared. The results showed that there is a large difference in the normal pupil size between teenagers and geriatric people. After dilation the difference in pupil size was statistically significant among the two groups. The study concludes that the pupillary dilation produced by administering 0.8% Tropicamide and 5% Phenylephrine produces higher mydriatic effect in teenagers than geriatric people

Upper limit on spontaneous supercurrents in Sr2_2RuO4_4

It is widely believed that the perovskite Sr$_2$RuO$_4$ is an unconventional superconductor with broken time reversal symmetry. It has been predicted that superconductors with broken time reversal symmetry should have spontaneously generated supercurrents at edges and domain walls. We have done careful imaging of the magnetic fields above Sr$_2$RuO$_4$ single crystals using scanning Hall bar and SQUID microscopies, and see no evidence for such spontaneously generated supercurrents. We use the results from our magnetic imaging to place upper limits on the spontaneously generated supercurrents at edges and domain walls as a function of domain size. For a single domain, this upper limit is below the predicted signal by two orders of magnitude. We speculate on the causes and implications of the lack of large spontaneous supercurrents in this very interesting superconducting system.Comment: 9 page

Precise Particle Tracking Against a Complicated Background: Polynomial Fitting with Gaussian Weight

We present a new particle tracking software algorithm designed to accurately track the motion of low-contrast particles against a background with large variations in light levels. The method is based on a polynomial fit of the intensity around each feature point, weighted by a Gaussian function of the distance from the centre, and is especially suitable for tracking endogeneous particles in the cell, imaged with bright field, phase contrast or fluorescence optical microscopy. Furthermore, the method can simultaneously track particles of all different sizes, and allows significant freedom in their shape. The algorithm is evaluated using the quantitative measures of accuracy and precision of previous authors, using simulated images at variable signal-to-noise ratios. To these we add a new test of the error due to a non-uniform background. Finally the tracking of particles in real cell images is demonstrated. The method is made freely available for non-commencial use as a software package with a graphical user-inferface, which can be run within the Matlab programming environment

The Halo Mass Function: High-Redshift Evolution and Universality

We study the formation of dark matter halos in the concordance LCDM model over a wide range of redshifts, from z=20 to the present. Our primary focus is the halo mass function, a key probe of cosmology. By performing a large suite of nested-box N-body simulations with careful convergence and error controls (60 simulations with box sizes from 4 to 256 Mpc/h, we determine the mass function and its evolution with excellent statistical and systematic errors, reaching a few percent over most of the considered redshift and mass range. Across the studied redshifts, the halo mass is probed over 6 orders of magnitude (10^7 - 10^13.5 M_sun/h). Historically, there has been considerable variation in the high redshift mass function as obtained by different groups. We have made a concerted effort to identify and correct possible systematic errors in computing the mass function at high redshift and to explain the discrepancies between some of the previous results. We discuss convergence criteria for the required force resolution, simulation box size, halo mass range, initial and final redshift, and time stepping. Because of conservative cuts on the mass range probed by individual boxes, our results are relatively insensitive to simulation volume, the remaining sensitivity being consistent with extended Press-Schechter theory. Previously obtained mass function fits near z=0, when scaled by linear theory, are in good agreement with our results at all redshifts, although a mild redshift dependence consistent with that found by Reed and collaborators exists at low redshifts.Comment: 20 pages, 15 figures. Minor changes to the text and figures; results and conclusions unchange

Method for Planning Graduate Programs in Construction Management

University programs in Western countries must be accredited, and although several detailed conceptual methods have aimed to design new programs, no specific quantitative tools are currently available. The purpose of this paper is to describe a method to plan, design, or improve graduate degree programs based on selected requirements and market demands. This method involves two metrics, which are later combined into a final index. The first metric is the completeness index that evaluates the extent to which certain programs cover a discipline, in this case, construction management, according to a model using two variables: infrastructure life cycle and organizational breakdown. The second metric is the adequacy index, which measures how a program addresses the previously identified market demands. The final indicator (summary index) relates both indexes in a plot chart. In this study, the applicability of the method is illustrated by a sample of 21 construction management programs from prestigious universities and a survey of the Spanish construction industry. It can be applied in practice, not only in the construction management field, but also in other fields with an appropriate theoretical model that maps each field of knowledge and exploratory data that highlight the demands of each specific market.Pellicer Armiñana, E.; Yepes Piqueras, V.; Ortega Llarena, AJ. (2013). Method for Planning Graduate Programs in Construction Management. Journal of Professional Issues in Engineering Education and Practice. 139(1):33-41. doi:10.1061/(ASCE)EI.1943-5541.0000120S3341139

Dimensionality Control of Electronic Phase Transitions in Nickel-Oxide Superlattices

The competition between collective quantum phases in materials with strongly correlated electrons depends sensitively on the dimensionality of the electron system, which is difficult to control by standard solid-state chemistry. We have fabricated superlattices of the paramagnetic metal LaNiO3 and the wide-gap insulator LaAlO3 with atomically precise layer sequences. Using optical ellipsometry and low-energy muon spin rotation, superlattices with LaNiO3 as thin as two unit cells are shown to undergo a sequence of collective metalinsulator and antiferromagnetic transitions as a function of decreasing temperature, whereas samples with thicker LaNiO3 layers remain metallic and paramagnetic at all temperatures. Metal-oxide superlattices thus allow control of the dimensionality and collective phase behavior of correlated-electron systems